Description of research activity:
Dendrimers with positively charged groups are also able to bind DNA/RNA, and by analogy with lipoplexes and polyplexes they are called dendriplexes. This class of polymers has structural advantages for gene transport. Dendrimers are monodisperse, stable, and are characterized by relatively low viscosity at high molecular mass and numerous end groups that can be ionized, which means that they can efficiently bind a large amount of genetic material. Our research activity is dendrimers in biology and medicine: studying DNA/RNA delivery using dendrimers. We characterize the interaction between DNA/RNA and dendrimers by biophysical techniques.
Keywords: Dendrimer, DNA, interaction, fluorescence, gel-electrophoresis
We study the interaction between DNA and dendrimers by biophysical techniques. We use fluorescence, fluorescent probes, gel-electrophoresis, phosphorescence.